Light-triggered hydrophilic drug release from liposomes through removal of a photolabile protecting group.

ABSTRACT: The antibiotic penicillin G cannot be completely incorporated into hydrophobic lipid-membranes owing to its hydrophilicity. Through modification with a hydrophobic and photolabile protecting group, penicillin G was effectively incorporated into liposomes and released by photoirradiation at 365 nm.

SUBMITTER: Goto Y 

PROVIDER: S-EPMC9059325 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature