Poly(trimethylene carbonate-co-valerolactone) copolymers are materials with tailorable properties: from soft to thermoplastic elastomers.

ABSTRACT: Aliphatic poly(ester-carbonates) are receiving extensive research attention as tailorable materials suitable for multiple applications from tissue engineering and 3D scaffold printing to drug delivery. Thus, simple reliable procedures for producing easily tailorable poly(ester-carbonates) without metal residues are continuously sought after. In this work, we report on one-pot synthesis of random copolymers of TMC and δ-VL using metal-free biocompatible 1,5,7-triazabicyclo[4.4.0]dec-5-ene as a catalyst and benzyl alcohol and poly(ethylene oxide) as initiators. Random poly(ester-carbonates) with TMC : VL unit ratios ranging from 80 : 20 to 20 : 80 were synthesized via ring-opening polymerization while displaying excellent agreement of comonomers' ratios in the feed and copolymer chain

SUBMITTER: Reinisova L 

PROVIDER: S-EPMC9059556 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature