Socioeconomic status impacts blood pressure response to positive airway pressure treatment.

ABSTRACT:

Study objectives

Positive airway pressure (PAP) treatment of obstructive sleep apnea reduces blood pressure (BP). Retrospective data suggest that African Americans (AA), a group at high-risk for hypertensive organ dysfunction, may have a greater BP response to PAP therapy than European Americans (EA). We examined the difference in 24-hour BP response to 3 months of PAP treatment between AA and EA.

Methods

Participants (n = 259, 161 AA and 98 EA) with apnea-hypopnea index ≥ 15 events/h from 2 prospective cohorts were included. t-Tests and multiple linear regression were used to examine BP outcomes in AA vs EA, adjusting for PAP adherence, socioeconomic status, and baseline characteristics.

Results

Participants were middle aged (mean ± SD, 53.8 ± 9.3 years), 86%

SUBMITTER: Imayama I 

PROVIDER: S-EPMC9059597 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature