Time-related aortic inflammatory response, as assessed with ¹⁸F-FDG PET/CT, in patients hospitalized with severely or critical COVID-19: the COVAIR study.

ABSTRACT:

Aim

Arterial involvement has been implicated in the coronavirus disease of 2019 (COVID-19). Fluorine 18-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) imaging is a valuable tool for the assessment of aortic inflammation and is a predictor of outcome. We sought to prospectively assess the presence of aortic inflammation and its time-dependent trend in patients with COVID-19.

Methods

Between November 2020 and May 2021, in this pilot, case-control study, we recruited 20 patients with severe or critical COVID-19 (mean age of 59 ± 12 years), while 10 age and sex-matched individuals served as the control group. Aortic inflammation was assessed by measuring ¹⁸F-FDG uptake in PET/CT performed 20-120 days post-admission. Global aortic

SUBMITTER: Vlachopoulos C 

PROVIDER: S-EPMC9059681 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature