An appraisal of laboratory models of androgenetic alopecia: A systematic review.

ABSTRACT:

Background

Androgenetic alopecia (AGA) is the most common form of non-scarring alopecia in humans. Several studies have used different laboratory models to study the pathogenesis and interventions for AGA. These study models have proved beneficial and have led to the approval of two drugs. However, the need to build on existing knowledge remains by examining the relevance of study models to the disease.

Objective

We sought to appraise laboratory or pre-clinical models of AGA.

Method

We searched through databases (PubMed, ScienceDirect, Web of Science, World CAT, Scopus and Google Scholar) for articles on AGA-related studies from 1942 to March 2019 with a focus on study models.

Results

The search rendered 101 studies after screening and deduplication. Several st

SUBMITTER: Ntshingila S 

PROVIDER: S-EPMC9060143 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature