The photobiology of the human circadian clock.
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ABSTRACT:
SUBMITTER: Schoonderwoerd RA
PROVIDER: S-EPMC9060497 | biostudies-literature | 2022 Mar
REPOSITORIES: biostudies-literature
Publications
The photobiology of the human circadian clock.
Schoonderwoerd Robin A RA de Rover Mischa M Janse Jan A M JAM Hirschler Lydiane L Willemse Channa R CR Scholten Leonie L Klop Ilse I van Berloo Sander S van Osch Matthias J P MJP Swaab Dick F DF Meijer Johanna H JH
Proceedings of the National Academy of Sciences of the United States of America 20220321 13
SignificanceThe function of our biological clock is dependent on environmental light. Rodent studies have shown that there are multiple colors that affect the clock, but indirect measures in humans suggest blue light is key. We performed functional MRI studies in human subjects with unprecedented spatial resolution to investigate color sensitivity of our clock. Here, we show that narrowband blue, green, and orange light were all effective in changing neuronal activity of the clock. While the clo ...[more]
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