Effect of alternan versus chitosan on the biological properties of human mesenchymal stem cells.

ABSTRACT: Alternan, an α-1,3- and α-1,6-linked glucan, is a polysaccharide that is produced by bacteria. Although the structure of alternan used in this study, an α-1,3- and α-1,6-linked glucan (hereafter referred to as alternan), has been comprehensively characterized, its function on cell biology, especially relative to cell growth and differentiation, has not been fully elucidated. In this study, we set forth to compare the effect of alternan versus chitosan on the biological properties of human mesenchymal stem cells (MSCs). The effect of chitosan on MSC differentiation has already been well characterized. The treated cells were determined for cell proliferation and differentiation capacity compared to untreated cells. The result showed that treatment by alternan or chitosan increased cel

SUBMITTER: Charoenwongpaiboon T 

PROVIDER: S-EPMC9060545 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature