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A novel nitrogen heterocycle platform-based highly selective and sensitive fluorescence chemosensor for the detection of Al³⁺ and its application in cell imaging.

ABSTRACT: In the study, a highly selective and sensitive fluorescence sensor derived from nitrogen heterocycle was synthesized and characterized. By the fluorescence experiments, it was found to show a higher response toward Al³⁺ than other commonly coexistent metal ions in C₂H₅OH/H₂O media (pH = 7.2). Moreover, the large binding constant (3.44 × 10¹⁴ M^-1) between Al³⁺ and the sensor was calculated by fluorescence titration experiment. In addition, the synergistic effect mechanism due to photoinduced electron transfer (PET) and C[double bond, length as m-dash]N isomerization was deduced according to the fluorescence behavior. In addition, the fluorescence imaging in living cells was studied systemically, which exhibited high fluorescence sensing activity toward Al³⁺.

SUBMITTER: Liu Z

PROVIDER: S-EPMC9060657 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature

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A novel nitrogen heterocycle platform-based highly selective and sensitive fluorescence chemosensor for the detection of Al3+ and its application in cell imaging.

Liu Zengchen Z Li Shujing S Ge Genwu G Li Yanxia Y Zhao Chunxiang C Zhang Hui H Yang Zhiguang Z

RSC advances 20190212 10

In the study, a highly selective and sensitive fluorescence sensor derived from nitrogen heterocycle was synthesized and characterized. By the fluorescence experiments, it was found to show a higher response toward Al3+ than other commonly coexistent metal ions in C2H5OH/H2O media (pH = 7.2). Moreover, the large binding constant (3.44 × 1014 M-1) between Al3+ and the sensor was calculated by fluorescence titration exper ...[more]

PMID: 35515938

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