The PANDORA Study: Prevalence and Outcome of Acute Hypoxemic Respiratory Failure in the Pre-COVID-19 Era.

ABSTRACT:

Objectives

To establish the epidemiological characteristics, ventilator management, and outcomes in patients with acute hypoxemic respiratory failure (AHRF), with or without acute respiratory distress syndrome (ARDS), in the era of lung-protective mechanical ventilation (MV).

Design

A 6-month prospective, epidemiological, observational study.

Setting

A network of 22 multidisciplinary ICUs in Spain.

Patients

Consecutive mechanically ventilated patients with AHRF (defined as Pao₂/Fio₂ ≤ 300 mm Hg on positive end-expiratory pressure [PEEP] ≥ 5 cm H₂O and Fio₂ ≥ 0.3) and followed-up until hospital discharge.

Interventions

None.

Measurements and main results

Primary outcomes were prevalence of AHRF and ICU mo

SUBMITTER: Villar J 

PROVIDER: S-EPMC9061169 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature