Synthesis and characterisation of α-carboxynitrobenzyl photocaged l-aspartates for applications in time-resolved structural biology.

ABSTRACT: We report a new synthetic route to a series of α-carboxynitrobenzyl photocaged l-aspartates for application in time-resolved structural biology. The resulting compounds were characterised in terms of UV/Vis absorption properties, aqueous solubility and stability, and photocleavage rates (τ = μs to ms) and quantum yields (φ = 0.05 to 0.14).

SUBMITTER: Zaitsev-Doyle JJ 

PROVIDER: S-EPMC9061760 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature