Efficacy of 0.01% low dose atropine and its correlation with various factors in myopia control in the Indian population.

ABSTRACT: We aimed to evaluate the efficacy and safety of low-dose atropine compared to placebo in the Indian population and also to study the impact of various modifiable and non-modifiable factors on myopia progression (MP) and drug efficacy (DE). It was a single-centre prospective placebo-controlled interventional study. 43 participants aged 6-16 years with progressive myopia received 0.01% atropine in the right eyes (treatment) and placebo in the left eyes (control) for 1-year. The main outcome measures were annual MP and axial length elongation (ALE) in treatment and control eyes and their percentage difference between two eyes (drug efficacy). Secondary outcome measures were the occurrence of any adverse events and the correlation of MP, ALE, and DE with various factors. 40 participants (80 ey

SUBMITTER: Chaurasia S 

PROVIDER: S-EPMC9061826 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature