Construction of self-signal DNA electrochemical biosensor employing WS₂ nanosheets combined with PIn6COOH.

ABSTRACT: In this work, a novel self-signal DNA electrochemical biosensor was constructed based on tungsten disulfide (WS₂) nanosheets combined with poly(indole-6-carboxylic acid) (PIn6COOH) as the sensing interface. The WS₂ nanosheets were synthesized via a simple solvent exfoliation method from bulk WS₂, and then PIn6COOH was electropolymerized on the WS₂ nanosheet-modified carbon paste electrode to obtain a unique nanocomposite. The electropolymerization efficiency was remarkably improved, ascribed to the physical adsorption between WS₂ nanosheets and aromatic In6COOH monomers, resulting in an increase of the electrochemical response of PIn6COOH. Owing to the presence of π-π interactions between the conjugated PIn6COOH/WS₂ n

SUBMITTER: Yang J 

PROVIDER: S-EPMC9062153 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature