COVID-19-related dynamic coagulation disturbances and anticoagulation strategies using conventional D-dimer and point-of-care Sonoclot tests: a prospective cohort study.

ABSTRACT:

Objectives

Coagulation changes associated with COVID-19 suggest the presence of a hypercoagulable state with pulmonary microthrombosis and thromboembolic complications. We assessed the dynamic association of COVID-19-related coagulation abnormalities with respiratory failure and mortality.

Design

Single-centre, prospective cohort study with descriptive analysis and logistic regression.

Setting

Tertiary care hospital, North India.

Participants

Patients with COVID-19 pneumonia requiring intensive care unit (ICU) admission between August 2020 and November 2020.

Primary and secondary outcome measures

We compared the coagulation abnormalities using standard coagulation tests like prothrombin time, D-dimer, platelet count, etc and point-of-care global coagulat

SUBMITTER: Premkumar M 

PROVIDER: S-EPMC9062462 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature