Inorganic nitrate supplementation and blood flow restricted exercise tolerance in post-menopausal women.

ABSTRACT: Exercise tolerance appears to benefit most from dietary nitrate (NO₃^-) supplementation when muscle oxygen (O₂) availability is low. Using a double-blind, randomized cross-over design, we tested the hypothesis that acute NO₃^- supplementation would improve blood flow restricted exercise duration in post-menopausal women, a population with reduced endogenous nitric oxide bioavailability. Thirteen women (57-76 yr) performed rhythmic isometric handgrip contractions (10% MVC, 30 per min) during progressive forearm blood flow restriction (upper arm cuff gradually inflated 20 mmHg each min) on three study visits, with 7-10 days between visits. Approximately one week following the first (familiarization) visit, participants consumed 140 ml of N

SUBMITTER: Proctor DN 

PROVIDER: S-EPMC9062890 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature