Enantioselective conjugate hydrosilylation of α,β-unsaturated ketones.

ABSTRACT: Enantioselective conjugate hydrosilylation of β,β-disubstituted α,β-unsaturated ketones was realized. In the presence of a chiral picolinamide-sulfonate Lewis base catalyst, the reactions provided various chiral ketones bearing a chiral center at the β-position in up to quantitative yields with moderate enantioselectivities.

SUBMITTER: Yang H 

PROVIDER: S-EPMC9063358 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature