Ontology highlight
ABSTRACT:
SUBMITTER: Kang JW
PROVIDER: S-EPMC9063500 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Kang Jing-Wen JW Li Xiang X Chen Fei-Yu FY Luo Yuan Y Zhang Shu-Cang SC Kang Bin B Peng Cheng C Tian Xu X Han Bo B
RSC advances 20190417 22
Protecting group-controlled annulations of tetra-substituted oxindole olefins and sulfur ylides have been achieved for the synthesis of multifunctional cyclopropane- and dihydrofuran-fused spirooxindoles. Under precise annulation regulation, a variety of cyclopropane- and dihydrofuran-fused spirooxindoles containing vicinal quaternary carbon centers were produced in up to 90% yield with up to 20 : 1 dr. This reaction demonstrates high regio-, chemo- and diastereoselectivity, broad functional gro ...[more]