Effect of ion form of the ion-exchange resin on ε-poly-l-lysine purification from microbial fermentation broth.

ABSTRACT: ε-Poly-l-lysine (ε-PL) is an added-value natural product with widespread application in the fields of food, pharmaceuticals and biopolymer materials. However, the high production cost reduces its application. To improve the efficiency of ε-PL purification for decreasing the cost of downstream processes, the ion form of the ion-exchange resin, which is widely used for ε-PL purification, was investigated systematically in this study. Among eleven cation-exchange resins tested, the Amberlite IRC-50 resin offered the best adsorption capability and the highest desorption ratio. The adsorption kinetics of IRC-50 resin with H⁺, Na⁺ and NH₄ ⁺ ion forms followed a pseudo-second-order model. The dynamic adsorption and desorption parameters of ε-PL were opt

SUBMITTER: Chen X 

PROVIDER: S-EPMC9063540 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature