Experimental and computational investigation of a DNA-shielded 3D metal-organic framework for the prompt dual sensing of Ag⁺ and S².

ABSTRACT: We herein report an efficient Ag⁺ and S^2- dual sensing scenario by a three-dimensional (3D) Cu-based metal-organic framework [Cu(Cdcbp)(bpea)] _n (MOF 1, H₃CdcbpBr = 3-carboxyl-(3,5-dicarboxybenzyl)-pyridinium bromide, bpea = 1,2-di(4-pyridinyl)ethane) shielded with a 5-carboxytetramethylrhodamine (TAMRA)-labeled C-rich single-stranded DNA (ss-probe DNA, P-DNA) as a fluorescent probe. The formed MOF-DNA probe, denoted as P-DNA@1, is able to sequentially detect Ag⁺ and S^2- in one pot, with detection limits of 3.8 nM (for Ag⁺) and 5.5 nM (for S^2-), which are much more lower than the allowable Ag⁺ (0.5 μM) and S^2- (0.6 μM) concentration in drinking water as regulated by World He

SUBMITTER: Cai SL 

PROVIDER: S-EPMC9064208 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature