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Visible-light-triggered supramolecular valves based on β-cyclodextrin-modified mesoporous silica nanoparticles for controlled drug release.

ABSTRACT: A high-efficiency drug delivery system has been successfully constructed based on visible-light triggered binding and releasing between tetra-ortho-methoxy-substituted azobenzene (mAzo) and β-cyclodextrin (β-CD) modified mesoporous silica nanoparticles. The drug releasing efficiency is calculated to be 56%. The high-efficiency visible-light-triggered drug delivery system may afford great potential for cancer therapy.

SUBMITTER: Bian Q

PROVIDER: S-EPMC9064457 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature

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Visible-light-triggered supramolecular valves based on β-cyclodextrin-modified mesoporous silica nanoparticles for controlled drug release.

Bian Qing Q Xue Zhaolu Z Sun Po P Shen Kejing K Wang Shangbing S Jia Juanying J

RSC advances 20190501 30

A high-efficiency drug delivery system has been successfully constructed based on visible-light triggered binding and releasing between tetra-<i>ortho</i>-methoxy-substituted azobenzene (mAzo) and β-cyclodextrin (β-CD) modified mesoporous silica nanoparticles. The drug releasing efficiency is calculated to be 56%. The high-efficiency visible-light-triggered drug delivery system may afford great potential for cancer therapy. ...[more]

PMID: 35519886

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