A novel ultrasensitive surface plasmon resonance-based nanosensor for nitrite detection.

ABSTRACT: Nitrite is a common food additive, however, its reduction product, nitrosamine, is a strong carcinogen, and hence the ultra-sensitive detection of nitrite is an effective means to prevent related cancers. In this study, different sized gold nanoparticles (AuNPs) were modified with P-aminothiophenol (ATP) and naphthylethylenediamine (NED). In the presence of nitrite, satellite-like AuNPs aggregates formed via the diazotization coupling reaction and the color of the system was changed by the functionalized AuNPs aggregates. The carcinogenic nitrite content could be detected by colorimetry according to the change in the system color. The linear concentration range of sodium nitrite was 0-1.0 μg mL^-1 and the detection limit was determined to be 3.0 ng mL^-1.

SUBMITTER: Miao P 

PROVIDER: S-EPMC9064595 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature