Fe³⁺-codoped ultra-small NaGdF₄:Nd³⁺ nanophosphors: enhanced near-infrared luminescence, reduced particle size and bioimaging applications.

ABSTRACT: Small-sized lanthanide-doped nanoparticles (NPs) exhibiting superior near-infrared (NIR) luminescence properties are highly desired for bioimaging applications. Herein, Fe³⁺ ions are codoped in NaGdF₄:Nd³⁺ nanocrystals via a simple coprecipitation method, which can simultaneously reduce the particle size and enhance the downconverting NIR luminescence of the NPs. The NIR luminescence intensity reaches the maximum for the obtained sub-5 nm NPs when the doping concentration of Fe³⁺ is tuned to 20 mol%, which is ∼1.7 times higher than that of the pristine 8.7 nm NPs without Fe³⁺ doping. After being modified with targeting molecules, the ultra-small NaGdF₄:Nd³⁺,Fe³⁺ NPs were successfully applied as l

SUBMITTER: Li Y 

PROVIDER: S-EPMC9064632 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature