Blood protein profiles related to preterm birth and retinopathy of prematurity.

ABSTRACT:

Background

Nearly one in ten children is born preterm. The degree of immaturity is a determinant of the infant's health. Extremely preterm infants have higher morbidity and mortality than term infants. One disease affecting extremely preterm infants is retinopathy of prematurity (ROP), a multifactorial neurovascular disease that can lead to retinal detachment and blindness. The advances in omics technology have opened up possibilities to study protein expressions thoroughly with clinical accuracy, here used to increase the understanding of protein expression in relation to immaturity and ROP.

Methods

Longitudinal serum protein profiles the first months after birth in 14 extremely preterm infants were integrated with perinatal and ROP data. In total, 448 unique protein target

SUBMITTER: Danielsson H 

PROVIDER: S-EPMC9064798 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature