Emotional Distress, Targeted Rejection, and Antibody Production After Influenza Vaccination in Adolescence.

ABSTRACT:

Objective

The purpose of this study was to explore how both ongoing emotional distress and the experience of a targeted rejection over the past 6 months are associated with adolescents' antibody response to influenza virus vaccination. We predicted that experiencing a targeted rejection would amplify the hypothesized negative association between emotional distress and antibody response after vaccination.

Methods

Adolescent participants (N = 148) completed two study visits (mean [standard deviation] days between visits = 27.4 [1.8]). At the first visit, they provided blood samples, were administered the seasonal (2018-2019) quadrivalent influenza vaccine (Fluzone, Sanofi Pasteur), completed questionnaires, and participated in a semistructured interview. At the second visit, t

SUBMITTER: Corallo KL 

PROVIDER: S-EPMC9064924 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature