Prognostic value of echocardiography for heart failure and death in adults with chronic kidney disease.

ABSTRACT:

Background

Adults with chronic kidney disease (CKD) are at increased risk of heart failure (HF) morbidity and mortality. Despite well-characterized abnormalities in cardiac structure in CKD, it remains unclear how to optimally leverage echocardiography to risk stratify CKD patients.

Methods

We evaluated associations between echocardiographic parameters and risk of HF hospitalization and death using Cox proportional hazard models and forward selection with integrated discrimination improvement (IDI).

Results

The study included 3,505 participants enrolled in the Chronic Renal Insufficiency Cohort (CRIC) study. Mean age was 59 ± 11 years, HF prevalence was 10%, and mean left ventricular (LV) ejection fraction (LVEF) was 54 ± 9%. During median 11 (interquartile range: 8-1

SUBMITTER: Fitzpatrick JK 

PROVIDER: S-EPMC9064944 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature