Effects of putrescine on gene expression in relation to physical barriers and antioxidant capacity in organs of weaning piglets.

ABSTRACT: Weaning stress can cause metabolic disorders, gastrointestinal dysfunction, physical barrier injury and disease susceptibility, thus leading to impaired growth and health of animals. Putrescine has the potential to reduce stress effects. However, the role of putrescine supplementation on barrier function and antioxidant capacity in animals' organs is largely unknown. This study evaluates the effects of putrescine on the physical barrier function, antioxidant status and related signalling molecule levels of weaning piglets' organs. A total of 24 weaning piglets were assigned to four treatment groups: (1) basal diet (control) and basal diets supplemented with (2) 0.05%, (3) 0.1% and (4) 0.15% putrescine. At the end of the 11 day experiment, ileum, liver, thymus and spleen samples were collec

SUBMITTER: Liu G 

PROVIDER: S-EPMC9065370 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature