Comparison of intensity modulated proton therapy beam configurations for treating thoracic esophageal cancer.

ABSTRACT:

Background and purpose

Specific proton-beam configurations are needed to spare organs at risk (OARs), including lungs, heart, and spinal cord, when treating esophageal squamous cell carcinoma (ESCC) in the thoracic region. This study aimed to propose new intensity-modulated proton therapy (IMPT) beam configurations and to demonstrate the benefit of IMPT compared with intensity-modulated x-ray therapy (IMXT) for treating ESCC.

Material and methods

IMPT plans with three different beam angle configurations were generated on CT datasets of 25 ESCC patients that were treated with IMXT. The IMPT beam designs were two commonly-used beam configurations (anteroposterior and posterior oblique) and a recently proposed beam configuration (anterosuperior with posteroinferior). The target

SUBMITTER: Oonsiri S 

PROVIDER: S-EPMC9065423 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature