A novel multi-reaction microdroplet platform for rapid radiochemistry optimization.
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ABSTRACT:
SUBMITTER: Rios A
PROVIDER: S-EPMC9065505 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Publications
A novel multi-reaction microdroplet platform for rapid radiochemistry optimization.
Rios Alejandra A Wang Jia J Chao Philip H PH van Dam R Michael RM
RSC advances 20190601 35
During the development of novel tracers for positron emission tomography (PET), the optimization of the synthesis is hindered by practical limitations on the number of experiments that can be performed per day. Here we present a microliter droplet chip that contains multiple sites (4 or 16) to perform reactions simultaneously under the same or different conditions to accelerate radiosynthesis optimization. ...[more]
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