Multi-staged gene expression profiling reveals potential genes and the critical pathways in kidney cancer.

ABSTRACT: Cancer is among the highly complex disease and renal cell carcinoma is the sixth-leading cause of cancer death. In order to understand complex diseases such as cancer, diabetes and kidney diseases, high-throughput data are generated at large scale and it has helped in the research and diagnostic advancement. However, to unravel the meaningful information from such large datasets for comprehensive and minute understanding of cell phenotypes and disease pathophysiology remains a trivial challenge and also the molecular events leading to disease onset and progression are not well understood. With this goal, we have collected gene expression datasets from publicly available dataset which are for two different stages (I and II) for renal cell carcinoma and furthermore, the TCGA and cBioPortal d

SUBMITTER: Khouja HI 

PROVIDER: S-EPMC9065671 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature