Cardiac computed tomography-derived myocardial tissue characterization after anthracycline treatment.

ABSTRACT:

Aims

Understanding cardiac function after anthracycline administration is very important from the perspective of preventing the onset of heart failure. Although cardiac magnetic resonance and echocardiography are recognized as the 'gold standard' for detecting cardiotoxicity, they have many shortcomings. We aimed to investigate whether cardiac computed tomography (CCT) could replace these techniques, assessing serial changes in cardiac tissue characteristics as determined by CCT after anthracycline administration.

Methods and results

We prospectively investigated 15 consecutive breast cancer patients who were scheduled to receive anthracycline therapy. We performed echocardiography and CCT before and 3, 6, and 12 months after anthracycline treatment. The mean cumulative admi

SUBMITTER: Egashira K 

PROVIDER: S-EPMC9065838 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature