Primary results from the Japanese Heart Failure and Sudden Cardiac Death Prevention Trial (HINODE).

ABSTRACT:

Aims

The HINODE study aimed to analyse rates of mortality, appropriately treated ventricular arrhythmias (VA), and heart failure in Japanese patients and compared with those in Western patients.

Methods and results

After treatment decisions following contemporary practice in Japan, patients were prospectively enrolled into four cohorts: (i) internal cardioverter-defibrillator (ICD), (ii) cardiac resynchronization therapy (CRT) defibrillator (CRT-D), (iii) standard medical therapy ('non-device': ND), or (iv) pacing (indicated for CRT; received pacemaker or CRT pacing). Cohorts 1-3 required a left ventricular ejection fraction ≤35%, a history of heart failure, and a need for primary prevention of sudden cardiac death based on two to five previously identified risk factors. End

SUBMITTER: Aonuma K 

PROVIDER: S-EPMC9065868 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature