Haemodynamic changes of interatrial shunting devices for heart failure: a systematic review and meta-analysis.

ABSTRACT:

Aims

To assess the efficacy and safety, primarily in relation to the haemodynamic effects, of interatrial shunting devices (ISD) for the treatment of heart failure (HF), we conducted a systematic review and a meta-analysis.

Methods and results

We used the MEDLINE, Cochrane Library, Embase, and PubMed databases to identify clinical studies (published to 4 August 2021) that evaluated the effect of ISD on HF. The primary endpoint was defined as changes in pulmonary capillary wedge pressure (PCWP). Secondary endpoints included (i) other haemodynamic indexes, including cardiac output (CO), right atrial pressure (RAP), and mean pulmonary artery pressure (mPAP) by right heart catheterization, and (ii) change from baseline in 6 min walk distance (6MWD). After a literature search and

SUBMITTER: Yi T 

PROVIDER: S-EPMC9065874 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature