Cohort-based long-term ozone exposure-associated mortality risks with adjusted metrics: A systematic review and meta-analysis.

ABSTRACT: Long-term ozone (O₃) exposure may lead to non-communicable diseases and increase mortality risk. However, cohort-based studies are relatively rare, and inconsistent exposure metrics impair the credibility of epidemiological evidence synthetization. To provide more accurate meta-estimations, this study updates existing systematic reviews by including recent studies and summarizing the quantitative associations between O₃ exposure and cause-specific mortality risks, based on unified exposure metrics. Cross-metric conversion factors were estimated linearly by decadal observations during 1990-2019. The Hunter-Schmidt random-effects estimator was applied to pool the relative risks. A total of 25 studies involving 226,453,067 participants (14 unique cohorts covering 99,855,

SUBMITTER: Sun HZ 

PROVIDER: S-EPMC9065904 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature