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Size dependent anti-invasiveness of silver nanoparticles in lung cancer cells.


ABSTRACT: The molecular mechanism of cancer cell death caused by silver nanoparticles (AgNPs) of different sizes is investigated. Compared with the larger nanoparticles, 13 nm AgNPs significantly inhibit the migration and invasiveness of lung adenocarcinoma A549 cells, induce elevated reactive oxygen species and lead to NF-κB directed cellular apoptosis.

SUBMITTER: Que YM 

PROVIDER: S-EPMC9066013 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature

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Size dependent anti-invasiveness of silver nanoparticles in lung cancer cells.

Que Yu Mei YM   Fan Xiao Qing XQ   Lin Xiao Juan XJ   Jiang Xiao Li XL   Hu Ping Ping PP   Tong Xiao Yong XY   Tan Qun You QY  

RSC advances 20190705 37


The molecular mechanism of cancer cell death caused by silver nanoparticles (AgNPs) of different sizes is investigated. Compared with the larger nanoparticles, 13 nm AgNPs significantly inhibit the migration and invasiveness of lung adenocarcinoma A549 cells, induce elevated reactive oxygen species and lead to NF-κB directed cellular apoptosis. ...[more]

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