Cloning and biochemical characterization of a class A beta-lactamase from Prevotella intermedia.

ABSTRACT: The gene encoding a beta-lactamase of Prevotella intermedia was cloned and sequenced. This gene, called cfxA2, shared 98% identity with cfxA, the structural gene of a beta-lactamase previously described in Bacteroides vulgatus. The deduced protein sequence had a K272E substitution. CfxA2 had the characteristics of class A, group 2e beta-lactamases.

SUBMITTER: Madinier I 

PROVIDER: S-EPMC90662 | biostudies-literature | 2001 Aug

REPOSITORIES: biostudies-literature