Sustaining Antimicrobial Stewardship in a High-Antibiotic Resistance Setting.

ABSTRACT:

Importance

There is a lack of studies comparing the intended and unintended consequences of prospective review and feedback (PRF) with computerized decision support systems (CDSS), especially in the longer term in antimicrobial stewardship.

Objective

To examine the outcomes associated with the sequential implementation of PRF and CDSS and changes to these interventions with long-term use of antibiotics for and incidence of multidrug resistant organisms (MDROs) and other unintended outcomes.

Design, setting, and participants

This cohort study used an interrupted time series with segmented regression analysis of data from January 2007 to December 2018. Data were extracted from the electronic medical records of patients admitted at a large university teaching hospital wi

SUBMITTER: Ng TM 

PROVIDER: S-EPMC9066280 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature