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The first eleven cases of SARS-CoV-2 Omicron variant infection in Japan: A focus on viral dynamics.


ABSTRACT: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant has spread rapidly worldwide. We report the clinical characteristics and threshold cycle (Ct) values of the first 11 patients infected with the SARS-CoV-2 Omicron variant in Japan. All patients were younger returnees from abroad; 10 patients had received two doses of vaccine. Estimated Ct values for the 11 patients were 6.0 (95% confidence interval [CI] 4.2-7.3) days for > 30, 10.6 (95% CI 9.5-11.9) days for > 35, 15.1 (95% CI 13.6-17.6) days for > 40, and 19.7 (95% CI 17.3- 23.7) days for > 45. Our results provide important insights for indicators of infection control.

SUBMITTER: Okumura N 

PROVIDER: S-EPMC9066457 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature

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The first eleven cases of SARS-CoV-2 Omicron variant infection in Japan: A focus on viral dynamics.

Okumura Nobumasa N   Tsuzuki Shinya S   Saito Sho S   Saito Tomoya T   Takasago Satoshi S   Hojo Masayuki M   Iwamoto Noriko N   Ohmagari Norio N  

Global health & medicine 20220401 2


The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant has spread rapidly worldwide. We report the clinical characteristics and threshold cycle (Ct) values of the first 11 patients infected with the SARS-CoV-2 Omicron variant in Japan. All patients were younger returnees from abroad; 10 patients had received two doses of vaccine. Estimated Ct values for the 11 patients were 6.0 (95% confidence interval [CI] 4.2-7.3) days for > 30, 10.6 (95% CI 9.5-11.9) days for > 35, 1  ...[more]

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