Mucosal healing of small intestinal stricture is associated with improved prognosis post-dilation in Crohn's disease.

ABSTRACT:

Background

Small intestinal stricture is a major cause for surgery in Crohn's disease (CD). Endoscopic balloon dilation (EBD) is performed for small intestinal strictures to avoid surgery, often repeatedly. However, factors that are associated with prognosis after EBD of small intestinal strictures remain poorly investigated. Mucosal healing is the therapeutic target in CD. We aimed to investigate the impact of mucosal healing defined by the presence of ulcers at the small intestinal stricture site on the prognosis of EBD in CD patients.

Methods

We retrospectively included patients with CD who underwent initial EBD for endoscopically impassable small intestinal strictures from January 2012 to March 2020 at a single center. The association between presence of ulcer at the str

SUBMITTER: Hibiya S 

PROVIDER: S-EPMC9066722 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature