Analysis of circRNA-miRNA-mRNA Regulatory Network in Peripheral Blood of Radiation Workers.

ABSTRACT: The health of radiation workers has always been our focus. Epidemiological investigation shows that long-term exposure to low-dose ionizing radiation can affect human health, especially cancer and cardiovascular disease, and there are many studies on it. However, up to now, there have been few reports on the research of blood and biological samples from radiation workers. In this study, radiation workers and healthy control groups were strictly screened, and the transcriptome of mRNA and circRNA was sequenced by extracting their peripheral venous blood. At the same time, appropriate data sets were selected in the GEO database for bioinformatics analysis, and circRNA-miRNA-mRNA network was constructed. We identified 9 different circular ribonucleic acids, 3 tiny ribonucleic acids, and 2 cen

SUBMITTER: Gao J 

PROVIDER: S-EPMC9067054 | biostudies-literature | 2022 Apr-Jun

REPOSITORIES: biostudies-literature