Loop Diuretic Prescription and 30-Day Outcomes in Older Patients With Heart Failure.

ABSTRACT:

Background

Heart failure (HF) is a major source of morbidity and mortality. Fluid retention and shortness of breath are its cardinal manifestations for which loop diuretics are used. Although their usefulness is well accepted, less is known about their role in improving clinical outcomes.

Objectives

The purpose of this study was to determine the relationship between loop diuretics and clinical outcomes in patients with HF.

Methods

Of the 25,345 older patients hospitalized for HF in the Medicare-linked OPTIMIZE-HF (Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure) registry, 9,866 (39%) received no pre-admission diuretics. The study excluded 1,083 patients receiving dialysis and 847 discharged on thiazide diuretics. Of the r

SUBMITTER: Faselis C 

PROVIDER: S-EPMC9067440 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature