Analysis of the different characteristics between omental preadipocytes and differentiated white adipocytes using bioinformatics methods.

ABSTRACT: Obesity is emerging as an epidemiological issue, being associated with the onset and progress of various metabolism-related disorders. Obesity is characterized by the white adipose expansion, which encounters white adipocyte hypertrophy and hyperplasia. White adipocyte hyperplasia is defined as adipogenesis with the increase in the number of the white adipocytes from the preadipocytes. Adipogenesis contributes to distributing excess triglycerides among the smaller newly formed adipocytes, reducing the number of hypertrophic adipocytes and secreting anti-inflammatory factor. Therefore, adipogenesis is emerging as a new therapeutic target for the treatment of obesity. In the present study, for a better understanding of the contribution of the alteration of the omental differentiated white ad

SUBMITTER: Yang X 

PROVIDER: S-EPMC9067510 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature