Simple clinical and laboratory predictors to improve empirical treatment strategies in areas of high scrub typhus and dengue endemicity, central Vietnam.

ABSTRACT:

Background

Dengue fever is highly endemic in Vietnam, but scrub typhus-although recognized as an endemic disease-remains underappreciated. These diseases together are likely to account for more than half of the acute undifferentiated fever burden in Vietnam. Scrub typhus (ST) is a bacterial disease requiring antimicrobial treatment, while dengue fever (DF) is of viral etiology and does not. The access to adequate diagnostics and the current understanding of empirical treatment strategies for both illnesses remain limited. In this study we aimed to contribute to the clinical decision process in the management of these two important etiologies of febrile illness in Vietnam.

Methods

Using retrospective data from 221 PCR-confirmed scrub typhus cases and 387 NS1 protein positive

SUBMITTER: Tran HTD 

PROVIDER: S-EPMC9067661 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature