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Ypsilandrosides U-Y, five new steroidal saponins from Ypsilandra thibetica.

ABSTRACT: Phytochemical reinvestigation on the whole plants of Ypsilandra thibetica obtained four new spirostanol glycosides, named ypsilandrosides U-X (1-4), and one new cholestanol glycoside, named ypsilandroside Y (5). Their structures have been established by extensive spectroscopic data and chemical methods. Among them, compound 4 is a rare spirostanol glycoside which possesses a novel 5(6 → 7) abeo-steroidal aglycone, while compound 1 is a first spirostanol bisdesmoside attached to C-3 and C-12, respectively, isolated from the genus Ypsilandra. The induced platelet aggregation activity of the isolates was tested.

SUBMITTER: Gao WT

PROVIDER: S-EPMC9068850 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature

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Ypsilandrosides U-Y, five new steroidal saponins from Ypsilandra thibetica.

Gao Wen-Tao WT Yu Ling-Ling LL Xie Jing J Xiao Long-Gao LG Zhang Shi-Juan SJ Ma Wen-Yi WY Yan Huan H Liu Hai-Yang HY

Natural products and bioprospecting 20220505 1

Phytochemical reinvestigation on the whole plants of Ypsilandra thibetica obtained four new spirostanol glycosides, named ypsilandrosides U-X (1-4), and one new cholestanol glycoside, named ypsilandroside Y (5). Their structures have been established by extensive spectroscopic data and chemical methods. Among them, compound 4 is a rare spirostanol glycoside which possesses a novel 5(6 → 7) abeo-steroidal aglycone, while compound 1 is a first spirostanol bisdesmoside attached to C-3 and C-12, res ...[more]

PMID: 35508749

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