Risk Assessment in Diffuse Large B-Cell Lymphoma by Combining Baseline Metabolic Tumor Volume and Peking Criteria When Evaluating Series ¹⁸F-Fluorodeoxyglucose Positron Emission Tomography Scans.

ABSTRACT: This study aimed to determine the predictive and prognostic value of baseline metabolic tumor volume (MTV) and the Peking criteria from serial positron emission tomography (PET) scans in diffuse large B-cell lymphoma, including 300 newly diagnosed patients who were prospectively treated with 2-4 cycles of standard first-line treatment (clinicaltrials.gov identifier: NCT02928861). PET/computed tomography (CT) examinations were performed at baseline, after two (PET-2) or four cycles (PET-4). PET during the interim was evaluated using Deauville 5-point scales (5-PS), ΔSUV_max criteria, and the Peking criteria which interpreted based on the maximum standard uptake of the liver (SUV_max-liver). Peking criteria had better accuracy, positive predictive value (PPV), and

SUBMITTER: Yuan T 

PROVIDER: S-EPMC9069109 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature