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The effect of non-oral hormonal contraceptives on hypertension and blood pressure: A systematic review and meta-analysis.


ABSTRACT: Oral contraceptives (OC) are associated with increased risk of hypertension and elevated blood pressure (BP). Whether non-oral hormonal contraceptives have similar associations is unknown. We sought to investigate the effect of non-oral hormonal contraceptive (NOHC) use on the risk of hypertension and changes in BP, compared to non-hormonal contraceptive and OC use. We searched bibliographic databases (MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials) until August 2020. Studies reporting risk of hypertension or changes in systolic and diastolic BP with NOHC use compared with either non-hormonal contraceptive or OC use. Abstract screening, full-text review, data extraction, and quality assessment were completed in duplicate. For studies reporting dichotomous outcomes, we repo

SUBMITTER: Kalenga CZ 

PROVIDER: S-EPMC9069167 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature