Amygdala responses to threat in violence-exposed children depend on trauma context and maternal caregiving.

ABSTRACT: Early life adversity (ELA) has been linked with increased arousal responses to threat, including increased amygdala reactivity. Effects of ELA on brain function are well recognized, and emerging evidence suggests that caregivers may influence how environmental stressors impact children's brain function. We investigated the hypothesis that positive interaction between mother and child can buffer against ELA effects on children's neural responses to threat, and related symptoms. N = 53 mother-child pairs (children ages 8-14 years) were recruited from an urban population at high risk for violence exposure. Maternal caregiving was measured using the Parenting Questionnaire and in a cooperation challenge task. Children viewed fearful and neutral face stimuli during functional magnetic resonance

SUBMITTER: Stevens JS 

PROVIDER: S-EPMC9069569 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature