The efficacy of vitamin D supplementation for irritable bowel syndrome: a systematic review with meta-analysis.

ABSTRACT:

Background

Irritable bowel syndrome (IBS) is a chronic gastrointestinal disorder involving gut-brain interactions with limited effective treatment options. Vitamin D deficiency is commonly observed in patients with IBS, but whether vitamin D supplementation ameliorates IBS is controversial in randomized controlled trials. The present systematic review and meta-analysis explored the efficacy of vitamin D supplementation in patients with IBS.

Methods

We performed a systematic search of potentially relevant publications from PubMed, EMBASE, the Cochrane Central Register of Controlled Studies and the Web of Science up until January 2022. We assessed the weighted mean difference (WMD) and 95% confidence interval (95% CI) of the IBS severity scoring system (IBS-SSS), IBS quality o

SUBMITTER: Huang H 

PROVIDER: S-EPMC9069731 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature