Functional Abnormality of the Executive Control Network in Individuals With Obesity During Delay Discounting.

ABSTRACT: Individuals with obesity (OB) prefer immediate rewards of food intake over the delayed reward of healthy well-being achieved through diet management and physical activity, compared with normal-weight controls (NW). This may reflect heightened impulsivity, an important factor contributing to the development and maintenance of obesity. However, the neural mechanisms underlying the greater impulsivity in OB remain unclear. Therefore, the current study employed functional magnetic resonance imaging with a delay discounting (DD) task to examine the association between impulsive choice and altered neural mechanisms in OB. During decision-making in the DD task, OB compared with NW had greater activation in the dorsolateral prefrontal cortex (DLPFC) and posterior parietal cortex, which was associa

SUBMITTER: Zhang W 

PROVIDER: S-EPMC9070347 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature