The interactions of human ovarian cancer cells and nanotextured surfaces: cell attachment, viability and apoptosis studies.

ABSTRACT: Understanding cell responses to the topography they are interacting with has a key role in designing surfaces due to the distinctiveness in the responses of different cell types. Thus far, a variety of surface textures have been fabricated, and the cellular responses of diversified cell lines to the surface textures have been assessed together with surface chemistry. However, the results reported in the literature are contradictory, and also not in-depth for inferring the relevance between cells, surface chemistry, and surface topography. Starting from this point of view, we focused on fabricating surfaces having extracellular matrix-like surface patterns and investigated the influence of patterning on human ovarian cancer cells. In this study, hemispherical protrusion-shaped, nanotextured

SUBMITTER: Yasayan G 

PROVIDER: S-EPMC9070382 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature