Notable paradoxical phenomena in associations between cardiovascular health score, subclinical and clinical cardiovascular disease in the community: The Framingham Heart Study.

ABSTRACT:

Importance

Cardiovascular Health (CVH) scores are inversely associated with prevalent subclinical (SubDz) and incident cardiovascular disease (CVD). However, the majority of people who develop CVD have intermediate or ideal CVH scores, while many with poor CVH profiles escape CVD development.

Objective

To describe the prevalence of paradoxical relations among CVH, SubDz, and CVD.

Design

Cohort study, Framingham Study data collected prospectively (1995-2016).

Setting

Population-based.

Participants

7,627 participants (mean age 49 years, 53% women) attending Offspring examinations 6/7 and Third Generation examinations 1/2.

Exposures

CVH score (range 0-14) constructed from poor, intermediate, or ideal status for each metric (smoking, diet, physical ac

SUBMITTER: Bourdillon MT 

PROVIDER: S-EPMC9070900 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature