Dataset Information
Retracted Article: Synthesis of deuterated isopentyl pyrophosphates for chemo-enzymatic labelling methods: GC-EI-MS based 1,2-hydride shift in epicedrol biosynthesis.
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ABSTRACT:
SUBMITTER: Said MS
PROVIDER: S-EPMC9071075 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Publications
Retracted Article: Synthesis of deuterated isopentyl pyrophosphates for chemo-enzymatic labelling methods: GC-EI-MS based 1,2-hydride shift in epicedrol biosynthesis.
RSC advances 20190909 48
A sesquiterpene epicedrol cyclase mechanism was elucidated based on the gas chromatography coupled to electron impact mass spectrometry fragmentation data of deuterated (<sup>2</sup>H) epicedrol analogues. The chemo-enzymatic method was applied for the specific synthesis of 8-position labelled farnesyl pyrophosphate and epicedrol. EI-MS fragmentation ions compared with non-labelled and isotopic mass shift fragments suggest that the <sup>2</sup>H of C6 migrates to the C7 position during the cycli ...[more]